Application Notes

Protein analysis for nitrogen generator applications

Recently, we visited a Shanghai-based scientific research institution conducting protein analysis to assess the performance and operation of PEAK Scientific’s LC-MS grade nitrogen generators in combination with a Thermo Scientific™ Orbitrap Eclipse™ mass spectrometer.

Converting Semivolatile GC-MS/MS Methods from He to N2 Carrier Gas with APGC,

Four common semivolatile applications were used to evaluate the performance of nitrogen carrier gas compared to helium using atmospheric pressure chemical ionization GC-APCI MS/MS.

Analysis of PFAS & Separation of Bile Salts by LC-MS/MS

Per- and polyfluoralkyl substances (PFAS) are a group of synthetic organofluoride compounds widely used in industry and consumer products, which are highly persistent and bioaccumulative, which has led to increased focus on their presence in the environment.

GC-MS Analysis of Phthalate esters using Hydrogen carrier gas

From July 22nd 2019, RoHS3 (directive 2015/863) added an update to the list of Phthalate esters included in the list of regulated substances. GC-MS is now the standard method for analysis of Phthalate esters.

Nitrogen saving vander graph table vs Helium

The Effect of Draw out Lens Diameter on Sensitivity of GC-MS Analysis

Following analysis of an essential oil mixture run using helium carrier gas with a standard ion volume and hydrogen carrier gas using a larger diameter draw-out lens across a range of flow rates, stabilization time, peak resolution, and signal-to-noise ratio were assessed.

Gas Chromatography Method List alternative to Helium

Gas Chromatography Method List - Alternatives to Helium Carrier Gas

This list details methods which can use a hydrogen generator or nitrogen generator for carrier gas for GC as an alternative to Helium.

Converting your GC carrier gas from helium to hydrogen : A step by step guide

Learn how to convert your GC carrier gas from helium to hydrogen with this step by step guide.

GC Used in Alcohol Profiling to Keep Consumers Safe

Learn how GC is used in Alcohol Profiling to ensure product quality and to keep consumers safe.

How does a Hydrogen generator work?

Find out how a hydrogen gas generator works and the answers to some common questions and misconceptions.

What is in e-cig liquid?

In a recent white paper, Restek corporation has identified a simple methodology for the simple comparison of e-cigarette liquids using GC-MS and GC-FID.

Benefits of Gas Generators Over Gas Cylinders : Expert opinion

The benefits of gas generators as alternatives to helium, such as the cost of gas generators, are discussed by Ed Connor. Giving his expert opinion on laboratory gas.

Method implications on lab gas supply for Residual Solvent Analysis using HS-GC-FID

Recently, there has been increased focus on use of nitrogen as an alternative carrier gas to helium, with small changes to methods along with shorter columns allowing identical analysis times.

The principles of ELSD

Find out the principles of ELSD and the gas delivery solutions for ELSD from a nitrogen gas generator. Optimizing ELSD is simple with a UHP nitrogen generator.

Use of Traps in GC

The Precision generator range has been designed to produce ultra-high purity (UHP) gases to supply GC applications for carrier and detector gas supply.

7 Steps to changing carrier gas from Helium to Hydrogen

How to change your lab gas from cylinder helium to on-site hydrogen gas generation

Analysis of drugs of abuse and explosives by GC-MS

The advantages that hydrogen offers as a cheap carrier gas include faster, improved analysis compared with helium.

FAMEs analysis method from helium to hydrogen for GC

Helium - Where it's at

Hydrogen is the most suitable alternative to helium for many analyses and it is likely to be adopted by GC labs because of its cost effectiveness and availability.

Blood Alcohol Content Analysis using Nitrogen Carrier Gas

FAMEs analysis method from helium to hydrogen for GC

Method revalidation can be simplified by keeping the new method as close to the old method as possible FAMEs

Cost-effective alternatives to helium for gas chromatography

Since the price of helium is set to continue to rise for the foreseeable future, labs can switch to more cost-effective alternatives such as hydrogen or nitrogen gas.

GC/MS analysis of a complex sample in DCM using hydrogen carrier gas

As well as lower price and unlimited availability, hydrogen has a number of potential advantages over helium, including potential for faster throughput, improved chromatography and better sample resolution.