Application Notes

Analysis of aromatic amines derived from Azo colorants using H2 carrier gas.

Azo dyes are extensively used in consumer products - including textiles, leather goods, clothing, and toys - with global demand measured in millions of tonnes annually. Because many azo dyes can release aromatic amines that are allergenic or carcinogenic, the European Union has restricted or banned those azo dyes capable of yielding any of the 14 aromatic amines classified as Category 1 or 2 carcinogens under Directive 76/769/EEC.

Maintaining Sensitivity and Spectral Integrity in GC-MS

Gas chromatography–mass spectrometry (GC-MS) remains a cornerstone analytical technique across diverse fields. Helium has been traditionally selected as the carrier gas of choice due to its inert nature and superior separation efficiency. However, helium’s rising cost and limited global availability have prompted the exploration of alternative carrier gases. Hydrogen is a compelling substitute.

Analysis of PFAS & Separation of Bile Salts by LC-MS/MS

Per- and polyfluoralkyl substances (PFAS) are a group of synthetic organofluoride compounds widely used in industry and consumer products, which are highly persistent and bioaccumulative, which has led to increased focus on their presence in the environment.

Converting Semivolatile GC-MS/MS Methods from He to N2 Carrier Gas with APGC,

Four common semivolatile applications were used to evaluate the performance of nitrogen carrier gas compared to helium using atmospheric pressure chemical ionization GC-APCI MS/MS.

Protein analysis for nitrogen generator applications

Recently, we visited a Shanghai-based scientific research institution conducting protein analysis to assess the performance and operation of PEAK Scientific’s LC-MS grade nitrogen generators in combination with a Thermo Scientific™ Orbitrap Eclipse™ mass spectrometer.

There's More to Achieving High Quality Results than a Top of the Line LC-MS

In pharmaceutical analysis, accuracy and consistency of results is essential in maintaining product quality, and as instrumentation becomes ever more sensitive, every material used in the analysis needs to feed into ensuring the best possible results.

GC analysis of e-liquid for impurities & nicotine using hydrogen carrier gas

Results of the analysis of e-Liquid by GC-MS using hydrogen carrier gas shows that a calibration curve of the active ingredient, nicotine, showed good linearity across a concentration range of 5-80 ppm.

Corona 1010 for Charged Aerosol Detection

Charged Aerosol Detection (CAD) is a detector with high sensitivity and good repeatability used to detect most non-volatile and semi-volatile organic compounds. Its uses cover a wide range of applications, including analysis of pharmaceutical ingredients, analysis of natural products, and analysis of sugars, proteins and surfactants.

Determining Low Levels of Chromium in Biological Samples by ICP-MS Using Hydrogen as Reaction Gas

Demonstrating the benefits of using hydrogen as a collision gas to remove the argon-carbide polyatomic interference in ICP-MS.

GC-MS Analysis of Phthalate esters using Hydrogen carrier gas

From July 22nd 2019, RoHS3 (directive 2015/863) added an update to the list of Phthalate esters included in the list of regulated substances. GC-MS is now the standard method for analysis of Phthalate esters.

Nitrogen saving vander graph table vs Helium

The Effect of Draw out Lens Diameter on Sensitivity of GC-MS Analysis

Following analysis of an essential oil mixture run using helium carrier gas with a standard ion volume and hydrogen carrier gas using a larger diameter draw-out lens across a range of flow rates, stabilization time, peak resolution, and signal-to-noise ratio were assessed.

Gas Chromatography Method List alternative to Helium

Gas Chromatography Method List - Alternatives to Helium Carrier Gas

This list details methods which can use a hydrogen generator or nitrogen generator for carrier gas for GC as an alternative to Helium.

Converting your GC carrier gas from helium to hydrogen : A step by step guide

Learn how to convert your GC carrier gas from helium to hydrogen with this step by step guide.

GC Used in Alcohol Profiling to Keep Consumers Safe

Learn how GC is used in Alcohol Profiling to ensure product quality and to keep consumers safe.

How does a Hydrogen generator work?

Find out how a hydrogen gas generator works and the answers to some common questions and misconceptions.

What is in e-cig liquid?

In a recent white paper, Restek corporation has identified a simple methodology for the simple comparison of e-cigarette liquids using GC-MS and GC-FID.

Benefits of Gas Generators Over Gas Cylinders : Expert opinion

The benefits of gas generators as alternatives to helium, such as the cost of gas generators, are discussed by Ed Connor. Giving his expert opinion on laboratory gas.

Method implications on lab gas supply for Residual Solvent Analysis using HS-GC-FID

Recently, there has been increased focus on use of nitrogen as an alternative carrier gas to helium, with small changes to methods along with shorter columns allowing identical analysis times.

The principles of ELSD

Find out the principles of ELSD and the gas delivery solutions for ELSD from a nitrogen gas generator. Optimizing ELSD is simple with a UHP nitrogen generator.

Use of Traps in GC

The Precision generator range has been designed to produce ultra-high purity (UHP) gases to supply GC applications for carrier and detector gas supply.

7 Steps to changing carrier gas from Helium to Hydrogen

How to change your lab gas from cylinder helium to on-site hydrogen gas generation