14th August 2023
Infinity XE nitrogen generator ticks all the boxes for the LSMBO
The BioOrganic Mass Spectrometry Laboratory (LSMBO) is part of the Institut Plurisciplinaire Hubert Curien at the University of Strasbourg, France. The LSMBO hosts an IBiSA-certified proteomic platform and is the Strasbourg branch of the French Proteomic Infrastructure (ProFI). The laboratory is known for developing new methods in proteomic analysis, bioinformatics, and structural mass spectrometry for the analysis of protein/protein interactions in large complexes.
We spoke with Jean-Marc Strub, an engineer at the LSMBO, to discuss their experience with their Infinity XE 5020.
Typically what is the focus of your LC-MS analysis - what sort of applications?
Proteomics studies on a wide range of organisms and tissues, but also supramolecular mass spectrometry and mAb with ligand.
What PEAK Scientific generators do you have in your laboratory and what LC-MS instruments do they supply?
We have the Infinity XE 5020.
We perform LC-MS analysis on different pumps like Waters (I-Class, H-Class, or M-Class), Agilent (1100 and 1200), and Thermo (Ultimate 3000) at a flow rate from 0.3µL/min to 250 µl/min. All these HPLC are coupled to mass spectrometers.
What prompted you to choose a PEAK generator for LC-MS and how long have you used it?
The choice was made on several criteria - flow rate, operating pressure & price. This new generator replaces an old PEAK generator whose gas flow was no longer sufficient for our experiments.
What has been the key benefit of deploying PEAK generators for LC-MS as opposed to your previous gas supply solution?
With our previous generator, the working pressure was sometimes under 6 bar because the consumption of gas was too high (>45-50 l/min) and some instruments are able to detect this low pressure and stop working for security reasons.
With the Infinity XE 5020 nitrogen generator this problem has disappeared.
How would you describe your purchasing experience with PEAK in terms of speed of response, ease of ordering, catering for your needs and timing of delivery?
Efficient and professional. The delivery took time because the generator was not available, but the installation was quick.
Have you ever had a site visit from a PEAK engineer in relation to your generator for LC-MS, if so, could you describe your experience of this support?
I have had one site visit from a PEAK engineer for the installation of the generator and, again, professionalism was the key takeaway.
Would you recommend PEAK Scientific generators to other laboratories - and if so, what would be your main reason for the recommendation?
Yes of course. Quality of the product, space requirement
Increase productivity with an Infinity XE nitrogen generator
The Infinity XE 50 series the LSMBO has in their lab is a nitrogen gas generator that can produce between 20-260 liters per minute of high-quality, laboratory-grade nitrogen gas.
Due to the high flow rate capabilities of the nitrogen generator, labs can confidently supply multiple instruments without seeing a dip in the performance of the nitrogen supply. The Infinity XE 5020 managed to eradicate this exact issue for the team at LSMBO.
Another benefit of the Infinity XE 50 series is its small footprint. Taking up little space in the lab, but supplying multiple instruments with the gas required means that you have more space for working and fewer hazards. As the generator does not have a built-in air compressor, it is effectively silent in operation.
The newest addition to the Infinity range of nitrogen gas generators
Released in 2021, the Infinity XE 60 series replaced the Infinity XE 50 series of nitrogen generators. With an increased flow rate of between 10-520 liters per minute, the Infinity XE 60 membrane nitrogen generators are even more comfortable supplying multiple instruments in your lab.
The Infinity XE 60 series has the ability to have its nitrogen output increased on-site, making it the perfect generator to grow alongside your lab. Even with concerns over space that the team at LSMBO had, the increase in nitrogen output does not affect the actual footprint of the nitrogen generator, meaning you can increase the flow of nitrogen to your instruments while maintaining the same footprint in the lab.
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